A Contribution on the Motor Nerve - Endings and on the Nekve - Endings in the M Uscle - Spindles

La& Atsirtant Drmanstrotw of Anatomy, in thc Mrdical Drpartmtnt of tht Univrrri/y of Michigan. By far the greater number of all the communications dealing with the ending of nerves in muscle tissues pertain to observations made on muscle tissue impregnated with one or the other of the several gold chloride methods; valuable as such observations have been, they yet leave many of the details more or less unsatisfactorily answered. Since the introduction of the chrome-silver and methylene blue methods, some further facts, tending to clear up some disputed points, have been gathered. A t the outstart however-and without in the least attempting to ' throw discredit on the many important observations which have been made with the Golgi method, greatly furthering our knowledge of the structure of the central and peripheral nervous system-it may be stated that so far as pertains to the relation of the ultimate endings of the nerve fibers to the structural elements of the several motor tissues, the Golgi method does not seem so applicable as its rival, the methylene blue method. The great advantage which this latter method has over both the gold chloride and the chrome-silver methods lies in the fact that in the most successful& sfaitied methylene blue preparations, only the nerve fibers and their ultimate endings are colored. while the other tissues remain practically ,un-stained. The observations on the endings of nerves in motor tissues made with the methylene blue method have revealed